Protective Effects of Cilastatin against Vancomycin-Induced Nephrotoxicity
نویسندگان
چکیده
منابع مشابه
Protective Effects of Cilastatin against Vancomycin-Induced Nephrotoxicity
Vancomycin is a very effective antibiotic for treatment of severe infections. However, its use in clinical practice is limited by nephrotoxicity. Cilastatin is a dehydropeptidase I inhibitor that acts on the brush border membrane of the proximal tubule to prevent accumulation of imipenem and toxicity. The aim of this study was to investigate the potential protective effect of cilastatin on vanc...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2015
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2015/704382